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Although membrane stress on viral capsids has been studied in both theoretical and experimental systems, few models exist for how a lipid bilayer interface can influence the structure and function of a virus. We modeled the effect of a lipid bilayer on the three-dimensional structure and stability of a virus using baculoviruses that encode a fluorescently-labeled reporter. We applied a combination of both theoretical and experimental approaches and discovered that the orientation of the membrane bilayer over the virion core changes both the stability of the virion and the rate at which non-specific covalent crosslinking of proteins takes place. Our study reveals an internal orientation of the bilayer membrane and the virion core that minimize membrane-induced structural perturbations.Q:
Can’t quite get jython to work, a noob Python programmer
I’m trying to start learning Python, after reading The New Beginning in the O’Reilly book. I’m using Windows 7, and am using the Python Visual Studio Express 2010 edition.
I have edited the PYTHONPATH variable so that it points to the python.exe and jython.exe files, but I still get errors. I have tried not setting the PYTHONPATH variable, and I get the same errors. Can someone please help? Thanks.
Here is the errors I get:
Traceback (most recent call last):
File “C:\Python26\jython\lib\encodings\cp437.py”, line 5, in decode
return codecs.charmap_decode(input,self.errors,decoding_table) UnicodeDecodeError: ‘charmap’ codec can’t decode byte 0x7f in position 3345: character maps to
Traceback (most recent call last):
File “C:\Python26\python.exe”, line 5, in
File “C:\Python26\jython.exe\sys.py”, line 15, in
import _winreg, winerror
File “C:\Python26\jython.exe\_winreg.py”, line 11
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